Application
Antibody used in WB on Transfected 293T at 0.2-1 ug/ml.| Product Name | TADA3L Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TADA3L, ADA3, NGG1, hADA3, STAF54, TADA3L |
| Product description | Adaptor proteins are usually required for transcriptional activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter.TADA3L is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis.Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined.1) Rual, J.F., (2005) Nature 437 (7062), 1173-1178. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TADA3L. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| TADA3L antibody can be used for detection of TADA3L by ELISA at 1:312500. TADA3L antibody can be used for detection of TADA3L by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | DogHumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TADA3 |
|---|---|
| Alternative Names | TADA3L ADA3 NGG1 hADA3 STAF54 TADA3L |
| Molecular Weight(MW) | 49 kDa |
Application
Antibody used in WB on Transfected 293T at 0.2-1 ug/ml.| Positive Control | 1) Tranfected 293T Cell Lysate |
|---|---|
| Application Notes | TADA3L antibody can be used for detection of TADA3L by ELISA at 1:312500. TADA3L antibody can be used for detection of TADA3L by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store TADA3L antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
