Taste receptor type 1 member 1, G-protein coupled receptor 70, TAS1R1, GPR70, T1R1, TR1
Product description
The protein encoded by this gene is a G protein-coupled
receptor and is a component of the heterodimeric amino acid taste
receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but
not to D-enantiomers or other compounds. Most amino acids that are
perceived as sweet activate T1R1+3, and this activation is strictly
dependent on an intact T1R1+3 heterodimer. Multiple transcript
variants encoding different isoforms have been found for this gene.1) Fushan, A.A., et al. Chem. Senses 35(7):579-592(2010)
Immunogen
This TAS1R1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323-351 amino acids from the Central region of human TAS1R1.
Western Blot at 1:1000 dilution Lane 1: A375 whole cell lysate Lane 2: NCI-H1299 whole cell lysate Lysates/proteins at 20 ug per lane.
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.