TBC1 domain family member 2A, Armus, Prostate antigen recognized and identified by SEREX 1, PARIS-1, TBC1D2, PARIS1, PP8997, TBC1D2A
Product description
TBC1D2 acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivativation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion.1) Letra, A., et al. Am. J. Med. Genet.152A (7), 1701-1710 (2010) :
Immunogen
This TBC1D2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 438-465 amino acids from the Central region of human TBC1D2.
Western blot analysis in mouse testis tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.