Tubulin-specific chaperone A, TCP1-chaperonin cofactor A, Tubulin-folding cofactor A, CFA, TBCA
Product description
The product of this gene is one of four proteins
(cofactors A, D, E, and C) involved in the pathway leading to
correctly folded beta-tubulin from folding intermediates. Cofactors
A and D are believed to play a role in capturing and stabilizing
beta-tubulin intermediates in a quasi-native confirmation. Cofactor
E binds to the cofactor D/beta-tubulin complex; interaction with
cofactor C then causes the release of beta-tubulin polypeptides
that are committed to the native state. This gene encodes
chaperonin cofactor A.1) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Immunogen
This TBCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-44 amino acids from the N-terminal region of human TBCA.
Western blot analysis in WiDr cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.