F-box-like/WD repeat-containing protein TBL1XR1, Nuclear receptor corepressor/HDAC3 complex subunit TBLR1, TBL1-related protein 1, Transducin beta-like 1X-related protein 1, TBL1XR1, IRA1, TBLR1
Product description
TBL1XR1 has sequence similarity
with members of the WD40 repeat-containing protein family. The WD40
group is a large family of proteins, which appear to have a
regulatory function. It is believed that the WD40 repeats mediate
protein-protein interactions and members of the family are involved
in signal transduction, RNA processing, gene regulation, vesicular
trafficking, cytoskeletal assembly and may play a role in the
control of cytotypic differentiation.1) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Immunogen
This TBL1XR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-137 amino acids from the N-terminal region of human TBL1XR1.
Western blot analysis in K562 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.