Application
Antibody used in IHC on Human kidney.Application
Antibody used in WB on Human Jurkat 5.0 ug/ml.| Product Name | TBX1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TBX1, DGS, TGA, VCF, CAFS, CTHM, DGCR, DORV, VCFS, TBX1C, CATCH22 |
| Product description | TBX1 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. TBX1 product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where TBX1 has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.1) Yamagishi, H., et al., (2003) Genes Dev. 17 (2), 269-281. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TBX1. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| TBX1 antibody can be used for detection of TBX1 by ELISA at 1:62500. TBX1 antibody can be used for detection of TBX1 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | TBX1 |
|---|---|
| Alternative Names | TBX1 DGS TGA VCF CAFS CTHM DGCR DORV VCFS TBX1C CATCH22 |
| Molecular Weight(MW) | 53 kDa |
Application
Antibody used in IHC on Human kidney.
Application
Antibody used in WB on Human Jurkat 5.0 ug/ml.| Positive Control | 1) Cat. No. 1205 - Jurkat Cell Lysate |
|---|---|
| Application Notes | TBX1 antibody can be used for detection of TBX1 by ELISA at 1:62500. TBX1 antibody can be used for detection of TBX1 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store TBX1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
