Application
Antibody used in WB on Human Jurkat 0.2-1 ug/ml.| Product Name | TBX19 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TBX19, FLJ26302, FLJ34543, TBS 19, TBS19, TPIT, dJ747L4.1 |
| Product description | TBX19 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx19/Tpit gene. Studies in mouse show that Tpit protein is present only in the two pituitary pro-opiomelanocortin (POMC)-expressing lineages, the corticotrophs and melanotrophs. Mutations in the human ortholog were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage.This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.1) Hochstrasser, D.F., (2007) J. Clin. Endocrinol. Metab. 92 (10), 3991-3999. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TBX19. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| TBX19 antibody can be used for detection of TBX19 by ELISA at 1:312500. TBX19 antibody can be used for detection of TBX19 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TBX19 |
|---|---|
| Alternative Names | TBX19 FLJ26302 FLJ34543 TBS 19 TBS19 TPIT dJ747L4.1 |
| Molecular Weight(MW) | 48 kDa |
Application
Antibody used in WB on Human Jurkat 0.2-1 ug/ml.| Positive Control | 1) Cat. No. 1205 - Jurkat Cell Lysate |
|---|---|
| Application Notes | TBX19 antibody can be used for detection of TBX19 by ELISA at 1:312500. TBX19 antibody can be used for detection of TBX19 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store TBX19 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
