Application
Western blot analysis of TENM1 in human brain tissue lysate with TENM1 antibody at 1 μg/ml.Application
Immunofluorescence of TENM1 in mouse brain tissue with TENM1 antibody at 20 μg/mL.Application
Immunohistochemistry of TENM1 in mouse brain tissue with TENM1 antibody at 5 μg/mL.| Product Name | TENM1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Teneurin transmembrane protein 1, teneurin-1, ODZ1, ODZ3, TEN-M1, TNM, TNM1 |
| Product description | The teneurin transmembrane protein 1 (TENM1) is a member of a family of four neuronal cell surface proteins homologous to the Drosophila pair-rule gene Ten-m (1,2). TENM1 is expressed primarily in the developing central nervous system and may be proteolytically cleaved with the intracellular domain translocating to the nucleus (3). TENM1 is a direct target of the homeobox transcription factor EMX2, a transcription factor thought to be important for area specification in the developing cortex (4).1) Minet AD, Rubin BP, Tucker RP, et al. Teneurin-1, a vertebrate homologue of the Drosophila pair-rule gene ten-m, is a neuronal protein with a novel type of heparin-binding domain. J. Cell Sci. 1999; 112:2019-32. |
| Immunogen | TENM1 antibody was raised against an 18 amino acid peptide near the amino terminus of human TENM1. The immunogen is located within the first 50 amino acids of TENM1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| TENM1 antibody can be used for detection of TENM1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TENM1 |
|---|---|
| Alternative Names | Teneurin transmembrane protein 1 teneurin-1 ODZ1 ODZ3 TEN-M1 TNM TNM1 |
| Molecular Weight(MW) | Predicted: 301 kDa Observed: 280 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Chicken: (83%) |
| Tissue Specificity | TENM1 antibody is human, mouse and rat reactive. TENM1 antibody is predicted to not cross-react with other members of the TENM family. |
| Entrez Gene | 10178 |
|---|---|
| Protein Accession | NP_001156750 |
Application
Western blot analysis of TENM1 in human brain tissue lysate with TENM1 antibody at 1 μg/ml.
Application
Immunofluorescence of TENM1 in mouse brain tissue with TENM1 antibody at 20 μg/mL.
Application
Immunohistochemistry of TENM1 in mouse brain tissue with TENM1 antibody at 5 μg/mL.| Positive Control | 1) Cat. No. 1303 - Human Brain Tissue Lysate |
|---|---|
| Application Notes | TENM1 antibody can be used for detection of TENM1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | TENM1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | TENM1 antibody is supplied in PBS containing 0.02% sodium azide. |
