Cancer-associated chromosomal changes often involve
regions containing fragile sites. This gene maps to a commom
fragile site on chromosome 7q31.2 designated FRA7G. This gene is
similar to mouse Testin, a testosterone-responsive gene encoding a
Sertoli cell secretory protein containing three LIM domains. LIM
domains are double zinc-finger motifs that mediate protein-protein
interactions between transcription factors, cytoskeletal proteins
and signaling proteins. Multiple protein isoforms are encoded by
transcript variants of this gene.1) Qiu, H., et al. Cancer Sci. 101(5):1255-1260(2010)
Immunogen
This TES antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from the N-terminal region of human TES.
Western blot analysis in K562 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.