Application
Immunohistochemistry of TFEB in human lung tissue with TFEB antibody at 2.5 μg/mL.Application
Immunofluorescence of TFEB in human lung tissue with TFEB antibody at 20 μg/mL.| Product Name | TFEB Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TFEB Antibody: TCFEB, BHLHE35, ALPHATFEB, Transcription factor EB, Class E basic helix-loop-helix protein 35, bHLHe35 |
| Product description | The Transcription factor EB (TFEB) is a member in the basic helix-loop-helix leucine zipper superfamily of transcription factors that is translocated in a subset of renal tumors (1,2). Recent studies have shown that lysosomal biogenesis is regulated by TFEB (3), which is in turn regulated by the mammalian target of rapamycin (mTOR) complex 1 (4). Other evidence suggests that TFEB coordinates the major steps of the autophagic pathway by driving the expression of autophagy and lysosomal genes (5).1) Carr CS and Sharp PA. A helix-loop-helix protein related to the immunoglobulin E box-binding proteins. Mol. Cell Biol. 1990; 10:4384-8. |
| Immunogen | Rabbit polyclonal TFEB antibody was raised against a 16 amino acid peptide near the carboxy terminus of human TFEB. The immunogen is located within amino acids 390 - 440 of TFEB. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-P |
| TFEB antibody can be used for detection of TFEB by immunohistochemistry at 2.5 μg/ml.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TFEB |
|---|---|
| Alternative Names | TFEB Antibody: TCFEB BHLHE35 ALPHATFEB Transcription factor EB Class E basic helix-loop-helix protein 35 bHLHe35 |
| Molecular Weight(MW) | N/A |
| Tissue Specificity | TFEB antibody is human specific. At least three isoforms of TFEB are known to exist. |
Application
Immunohistochemistry of TFEB in human lung tissue with TFEB antibody at 2.5 μg/mL.
Application
Immunofluorescence of TFEB in human lung tissue with TFEB antibody at 20 μg/mL.| Positive Control | 1) Cat. No. 10-101 - Human Lung Tissue Slide |
|---|---|
| Application Notes | TFEB antibody can be used for detection of TFEB by immunohistochemistry at 2.5 μg/ml.: |
| Form | Liquid |
|---|---|
| Storage Instructions | TFEB antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | TFEB antibody is supplied in PBS containing 0.02% sodium azide. |
