Application
Western Blot at 1:2000 dilution Lane 1: human testis lysate Lane 2: mouse lung lysate Lysates/proteins at 20 ug per lane.Application
Antibody staining TGFBR2 in human brain sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections).Application
Antibody staining TGFBR2 in human brain sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections).Application
Antibody staining TGFBR2 in Human spleen tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections).Application
Western Blot at 1:2000 dilution Lane 1: NCCIT whole cell lysates Lane 2: mouse lung lysates Lane 3: SW620 whole cell lysates Lysates/proteins at 20 ug per lane.Application
Western Blot at 1:1000 dilution + mouse lung lysates Lysates/proteins at 20 ug per lane.Application
Western Blot at 1:2000 dilution + mouse lung lysates Lysates/proteins at 20 ug per lane.| Product Name | TGFBR2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TGF-beta receptor type-2, TGFR-2, TGF-beta type II receptor, Transforming growth factor-beta receptor type II, TGF-beta receptor type II, TbetaR-II, TGFBR2 |
| Product description | This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.1) Inamoto, S., et al. Cardiovasc. Res. 88(3):520-529(2010) |
| Immunogen | This TGFBR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-40 amino acids from the N-terminal region of human TGFBR2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IFIHC-PWB |
| For IHC-P starting dilution is: 1:25 For WB starting dilution is: 1:1000: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TGFBR2 |
|---|---|
| Alternative Names | TGF-beta receptor type-2 TGFR-2 TGF-beta type II receptor Transforming growth factor-beta receptor type II TGF-beta receptor type II TbetaR-II TGFBR2 |
| Molecular Weight(MW) | 65 kDa |
Application
Western Blot at 1:2000 dilution Lane 1: human testis lysate Lane 2: mouse lung lysate Lysates/proteins at 20 ug per lane.
Application
Antibody staining TGFBR2 in human brain sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections).
Application
Antibody staining TGFBR2 in human brain sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections).
Application
Antibody staining TGFBR2 in Human spleen tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections).
Application
Western Blot at 1:2000 dilution Lane 1: NCCIT whole cell lysates Lane 2: mouse lung lysates Lane 3: SW620 whole cell lysates Lysates/proteins at 20 ug per lane.
Application
Western Blot at 1:1000 dilution + mouse lung lysates Lysates/proteins at 20 ug per lane.
Application
Western Blot at 1:2000 dilution + mouse lung lysates Lysates/proteins at 20 ug per lane.| Application Notes | For IHC-P starting dilution is: 1:25 For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
