Transglutaminases are enzymes that catalyze the
crosslinking of proteins by epsilon-gamma glutamyl lysine
isopeptide bonds. While the primary structure of transglutaminases
is not conserved, they all have the same amino acid sequence at
their active sites and their activity is calcium-dependent. The
protein encoded by this gene consists of two polypeptide chains
activated from a single precursor protein by proteolysis. The
encoded protein is involved the later stages of cell envelope
formation in the epidermis and hair follicle.1) Yamane, A., et al. FEBS J. 277(17):3564-3574(2010)
Immunogen
This TGM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 539-567 amino acids from the C-terminal region of human TGM3.
Protein-glutamine gamma-glutamyltransferase E Transglutaminase E TG(E) TGE TGase E Transglutaminase-3 TGase-3 Protein-glutamine gamma-glutamyltransferase E 50 kDa catalytic chain Protein-glutamine gamma-glutamyltransferase E 27 kDa non-catalytic ch
Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.