TGM5 belongs to the transglutaminase superfamily, transglutaminase family. It catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. It contributes to the formation of the cornified cell envelope of keratinocytes. Defects in TGM5 are a cause of peeling skin syndrome acral type (APSS).1) Cassidy, A.J., (2005) Am. J. Hum. Genet. 77 (6), 909-917.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TGM5.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAWB
TGM5 antibody can be used for detection of TGM5 by ELISA at 1:12500. TGM5 antibody can be used for detection of TGM5 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
TGM5 antibody can be used for detection of TGM5 by ELISA at 1:12500. TGM5 antibody can be used for detection of TGM5 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store TGM5 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.