Application
Western blot analysis of TGM7 in human lung tissue lysate with TGM7 antibody at 1 μg/mL.Application
Immunofluorescence of TGM7 in A549 cells with TGM7 antibody at 10 μg/mL.Application
Immunocytochemistry of TGM7 in A549 cells with TGM7 antibody at 2.5 μg/mL.| Product Name | TGM7 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | TGM7 Antibody: Transglutaminases (TGM) are a family of structurally and functionally related Ca2+-dependent enzymes (TGases) that stabilize protein assemblies through the formation of gamma-glutamyl-epsilon lysine crosslinks. TGases influence numerous biological processes, including blood coagulation, cell differentiation, fertilization and apoptosis. TGM7 belongs to the transglutaminase superfamily and is also thought to catalyze the cross-linking of proteins, often resulting in stabilization of protein assemblies. Little is known of the role of TGM7, but defects in the highly related protein TGM5 are associated with acral peeling skin syndrome.1) Ueki S, et al. Dual functions of transglutaminase in novel cell adhesion. J. Cell Sci. 1996; 109:2727-35 |
| Immunogen | TGM7 antibody was raised against a 13 amino acid synthetic peptide near the center of human TGM7. The immunogen is located within amino acids 460 - 510 of TGM7. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAICCIFWB |
| TGM7 antibody can be used for detection of TGM7 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μg/mL. For immunofluorescence start at 10 μg/mL. | |
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TGM7 |
|---|---|
| Alternative Names | TGM7 Antibody: TGMZ Protein-glutamine gamma-glutamyltransferase Z Transglutaminase Z TGZ |
| Sequence Similarities | 2) Cat. No. 17-003 - A549 Cell Slide |
| Tissue Specificity | TGM7 antibody is predicted to not cross-react with other TGase protein family members. At least two isoforms of TGM7 are known to exist; this antibody will recognize both isoforms. |
Application
Western blot analysis of TGM7 in human lung tissue lysate with TGM7 antibody at 1 μg/mL.
Application
Immunofluorescence of TGM7 in A549 cells with TGM7 antibody at 10 μg/mL.
Application
Immunocytochemistry of TGM7 in A549 cells with TGM7 antibody at 2.5 μg/mL.| Positive Control | 1) Cat. No. 1302 - Human Lung Tissue Lysate |
|---|---|
| Application Notes | TGM7 antibody can be used for detection of TGM7 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μg/mL. For immunofluorescence start at 10 μg/mL. |
| Form | Liquid |
|---|---|
| Storage Instructions | TGM7 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | TGM7 Antibody is supplied in PBS containing 0.02% sodium azide. |
