T-lymphoma invasion and metastasis-inducing protein 2, TIAM-2, SIF and TIAM1-like exchange factor, TIAM2, KIAA2016, STEF
Product description
This gene encodes a guanine nucleotide exchange factor. A
highly similar mouse protein specifically activates ras-related C3
botulinum substrate 1, converting this Rho-like guanosine
triphosphatase (GTPase) from a guanosine diphosphate-bound inactive
state to a guanosine triphosphate-bound active state. The encoded
protein may play a role in neural cell development. Alternatively
spliced transcript variants encoding different isoforms have been
described.1) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Immunogen
This TIAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 357-385 amino acids from the N-terminal region of human TIAM2.
Western blot analysis in mouse liver tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.