Application
Western Blot at 1:2000 dilution Lane 1: EL4 whole cell lysate Lane 2: human fetal thymus lysate Lane 3: human spleen lysate Lane 4: HUT78 whole cell lysate Lane 5: Jurkat whole cell lysate Lane 6: MOLT-4 whole cell lysate Lysates/proteins at 20 ug per lane.| Product Name | TIGIT Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | T-cell immunoreceptor with Ig and ITIM domains, V-set and immunoglobulin domain-containing protein 9, V-set and transmembrane domain-containing protein 3, TIGIT, VSIG9, VSTM3 |
| Product description | Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.1) Ota T.,et al.Nat. Genet. 36:40-45(2004). |
| Immunogen | This TIGIT antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 12-142 amino acids from human TIGIT. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:2000: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TIGIT |
|---|---|
| Alternative Names | T-cell immunoreceptor with Ig and ITIM domains V-set and immunoglobulin domain-containing protein 9 V-set and transmembrane domain-containing protein 3 TIGIT VSIG9 VSTM3 |
| Molecular Weight(MW) | 26 kDa |
Application
Western Blot at 1:2000 dilution Lane 1: EL4 whole cell lysate Lane 2: human fetal thymus lysate Lane 3: human spleen lysate Lane 4: HUT78 whole cell lysate Lane 5: Jurkat whole cell lysate Lane 6: MOLT-4 whole cell lysate Lysates/proteins at 20 ug per lane.| Application Notes | For WB starting dilution is: 1:2000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
