Tiparp is a poly [ADP-ribose] polymerase using NAD(+) as a substrate to transfer ADP-ribose onto glutamic acid residues of a protein acceptor; repeated rounds of ADP-ribosylation leads to the formation of poly(ADPribose) chains on the protein, thereby altering the function of the target protein. May play a role in the adaptative response to chemical exposure (TCDD) and thereby mediates certain effects of the chemicals.1) Schmahl, J., et al. Genes Dev. 22(23):3255-3267(2008)
Immunogen
This Tiparp antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-292 amino acids from the C-terminal region of human Tiparp.
Western Blot at 1:500 dilution + mouse kidney lysate Lysates/proteins at 20 ug per lane.
Application
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:500:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.