Application
Western blot analysis of TLR11 in RAW264.7 cell lysates with TLR11 antibody at (A) 0.5, (B) 1, and (C) 2 μg/mL.Application
Immunofluorescence of TLR11 in Raw264 cells with TLR11 antibody at 10 μg/mL.Application
Immunocytochemistry of TLR11 in RAW264.7 cells with TLR11 antibody at 10 μg/mL| Product Name | TLR11 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TLR11 Antibody: Gm287, Gm287, Toll-like receptor 11 |
| Product description | TLR11 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system.1) Vogel SN, Fitzgerald KA, and Fenton MJ. TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression. Mol. Interv. 2003; 3:466-77. |
| Immunogen | TLR11 antibody was raised against a peptide corresponding to 16 amino acids between the middle and carboxy terminus of mouse TLR11. The immunogen is located within the last 50 amino acids of TLR11. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAICCIFWB |
| TLR11 antibody polyclonal antibody can be used for detection of TLR11 by Western blot at 0.5 to 2 μg/mL. Antibody can also be used for immunocytochemistry starting at 10 μg/mL. For immunofluorescence start at 10 μg/mL.: |
|
| Species Reactivity | Mouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Tlr11 |
|---|---|
| Alternative Names | TLR11 Antibody: Gm287 Gm287 Toll-like receptor 11 |
| Sequence Similarities | 2) Cat. No. 17-203 - RAW 264.7 Cell Slide |
Application
Western blot analysis of TLR11 in RAW264.7 cell lysates with TLR11 antibody at (A) 0.5, (B) 1, and (C) 2 μg/mL.
Application
Immunofluorescence of TLR11 in Raw264 cells with TLR11 antibody at 10 μg/mL.
Application
Immunocytochemistry of TLR11 in RAW264.7 cells with TLR11 antibody at 10 μg/mL| Positive Control | 1) Cat. No. 1283 - RAW 264.7 Cell Lysate |
|---|---|
| Application Notes | TLR11 antibody polyclonal antibody can be used for detection of TLR11 by Western blot at 0.5 to 2 μg/mL. Antibody can also be used for immunocytochemistry starting at 10 μg/mL. For immunofluorescence start at 10 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | TLR11 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | TLR11 Antibody is supplied in PBS containing 0.02% sodium azide. |
