TMEM147 Antibody: NIFIE14, Transmembrane protein 147, Protein NIFIE 14
Product description
TMEM147 Antibody: TMEM147 is a recently identified protein that associates with Nicalin and NOMO, forming a complex that is thought to be similar to the gamma-secretase complex. TMEM147 localizes to the endoplasmic reticulum (ER), and in zebrafish, is expressed during early development. TMEM147 also interacts with the M3 muscarinic receptor (M3R) in the ER and is thought to negatively its expression and function.1) Dettmer U, Kuhn PH, Abou-Ajram C, et al. Transmembrane protein 147 (TMEM147) is a novel component of the Nicalin-NOMO protein complex. J. Biol. Chem. 2010; 285:26174-81
Immunogen
TMEM147 antibody was raised against a 13 amino acid synthetic peptide near the center of human TMEM147. The immunogen is located within amino acids 70 - 120 of TMEM147.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAWB
TMEM147 antibody can be used for detection of TMEM147 by Western blot at 1 - 2 μg/mL.:
Western blot analysis of TMEM147 in Daudi cell lysate with TMEM147 antibody at (A) 1 and (B) 2 μg/mL.
Positive Control
1) Cat. No. 1224 - Daudi Cell Lysate
Application Notes
TMEM147 antibody can be used for detection of TMEM147 by Western blot at 1 - 2 μg/mL.:
Additional Information
Form
Liquid
Storage Instructions
TMEM147 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer
TMEM147 Antibody is supplied in PBS containing 0.02% sodium azide.