Application
Western blot analysis of TMEM184A in rat brain tissue lysate with TMEM184A antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.Application
Immunohistochemistry of TMEM184A in human brain tissue with TMEM184A antibody at 5 μg/mL.| Product Name | TMEM184A Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TMEM184A Antibody: Transmembrane protein 184A |
| Product description | TMEM184A Antibody: TMEM184A, a multi-pass transmembrane protein, belongs to the UPF0206 family. While the exact function of TMEM184A remains unclear, it is known to be expressed at high levels in the developing testis. TMEM184A may mediate sex-specific signaling events during Sertoli cell differentiation. The restricted expression of this gene in Sertoli cells suggests a role for the encoded protein in the development and/or continued function of that cell type. Ectopic expression of TMEM184A in female genital ridges resulted in failure of gonocytes to enter meiosis.1) Svingen T, Beverdam A, Bernard P, et al. Sex-specific expression of a novel gene Tmem184a during mouse testis differentiation. Reproduction2007; 133:983-9. |
| Immunogen | TMEM184A antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human TMEM184A. The immunogen is located within the last 50 amino acids of TMEM184A. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHC-PWB |
| TMEM184A antibody can be used for detection of TMEM184A by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TMEM184A |
|---|---|
| Alternative Names | TMEM184A Antibody: Transmembrane protein 184A |
| Molecular Weight(MW) | Predicted: 45 kDa Observed: 52 kDa |
| Sequence Similarities | 2) Cat. No. 10-301 - Human Brain Tissue Slide |
| Entrez Gene | 202915 |
|---|---|
| Protein Accession | NP_001091089 |
Application
Western blot analysis of TMEM184A in rat brain tissue lysate with TMEM184A antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Application
Immunohistochemistry of TMEM184A in human brain tissue with TMEM184A antibody at 5 μg/mL.| Positive Control | 1) Cat. No. 1463 - Rat Brain Tissue Lysate |
|---|---|
| Application Notes | TMEM184A antibody can be used for detection of TMEM184A by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | TMEM184A antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | TMEM184A Antibody is supplied in PBS containing 0.02% sodium azide. |
