Application
Western blot analysis of TMEM204 in human brain tissue lysate with TMEM204 antibody at 1 μg/mL .Application
Immunofluorescence of TMEM204 in mouse brain tissue with TMEM204 antibody at 20 μg/mL.Application
Immunohistochemistry of TMEM204 in mouse brain tissue with TMEM204 antibody at 5 μg/mL.| Product Name | TMEM204 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TMEM204 Antibody: CLP24, C16orf30, CLP24, UNQ6509/PRO21434, Transmembrane protein 204, Claudin-like protein 24 |
| Product description | TMEM204 Antibody: Transmembrane protein 204 (TMEM204) is a four-transmembrane protein that is induced under hypoxic conditions. It localizes to cell-cell junctions and co-localizes with the beta-catenin adherens junction-associated protein, but not with tight junctions. Overexpression of TMEM204 results in decreased adhesion between cells, indicating that TMEM204 is an adherens junction protein that modulates cell adhesion and potentially angiogenesis. Recent evidence suggests TMEM204 may also be involved in epilepsy.1) Kearsey J, Petit S, De Oliveira C, et al. A novel four transmembrane spanning protein, CLP24. Eur. J. Biochem. 204; 271:2584-92. |
| Immunogen | TMEM204 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human TMEM204. The immunogen is located within the last 50 amino acids of TMEM204. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| TMEM204 antibody can be used for detection of TMEM204 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TMEM204 |
|---|---|
| Alternative Names | TMEM204 Antibody: CLP24 C16orf30 CLP24 UNQ6509/PRO21434 Transmembrane protein 204 Claudin-like protein 24 |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Bovine: (100%) |
| Tissue Specificity | At least two isoforms of TMEM204 are known to exist; this antibody will recognize both isoforms. |
Application
Western blot analysis of TMEM204 in human brain tissue lysate with TMEM204 antibody at 1 μg/mL .
Application
Immunofluorescence of TMEM204 in mouse brain tissue with TMEM204 antibody at 20 μg/mL.
Application
Immunohistochemistry of TMEM204 in mouse brain tissue with TMEM204 antibody at 5 μg/mL.| Positive Control | 1) Cat. No. 1303 - Human Brain Tissue Lysate |
|---|---|
| Application Notes | TMEM204 antibody can be used for detection of TMEM204 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | TMEM204 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | TMEM204 Antibody is supplied in PBS containing 0.02% sodium azide. |
