Application
Western blot analysis of TMIGD2 in mouse small intestine tissue lysate with TMIGD2 antibody at 1 μg/ml.Application
Immunohistochemistry of TMIGD2 in human small intestine tissue with TMIGD2 antibody at 5 μg/mL.| Product Name | TMIGD2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TMIGD2 Antibody: IGPR1, IGPR-1, IGPR1, UNQ3059/PRO9879, Transmembrane and immunoglobulin domain-containing protein 2, Immunoglobulin and proline-rich receptor 1 |
| Product description | TMIGD2 (transmembrane and immunoglobulin domain containing 1), also known as immunoglobulin-containing and proline-rich receptor 1 (IGPR1), is novel adhesion molecule that is expressed in multiple tissues, primarily in cells of epithelium and endothelium origins (1). TMIGD2 is thought to be involved in angiogenesis and regulates cellular morphology, homophilic cell aggregation, and cell-cell interaction. TMIGD2 activity also modulates actin stress fiber formation and focal adhesion and reduces cell migration (1).1) Rahimi N, Rezazadeh K, Mahoney JE, et al. Identification of IGPR-1 as a novel adhesion molecule involved in angiogenesis. Mol. Biol. Cell 2012; 23:1646-56. |
| Immunogen | TMIGD2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human TMIGD2. The immunogen is located within the last 50 amino acids of TMIGD2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHC-PWB |
| TMIGD2 antibody can be used for detection of TMIGD2 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TMIGD2 |
|---|---|
| Alternative Names | TMIGD2 Antibody: IGPR1 IGPR-1 IGPR1 UNQ3059/PRO9879 Transmembrane and immunoglobulin domain-containing protein 2 Immunoglobulin and proline-rich receptor 1 |
| Molecular Weight(MW) | Predicted: 31 kDa Observed: 26 kDa |
| Sequence Similarities | 2) Cat. No. 11-801 - Human Small Intestine Tissue Slide |
| Tissue Specificity | TMIGD2 antibody is human and mouse reactive. At least three isoforms of TMIGD2 are known to exist; this antibody will detect all three. TMIGD2 antibody is predicted to not cross-react with TMIGD1. |
Application
Western blot analysis of TMIGD2 in mouse small intestine tissue lysate with TMIGD2 antibody at 1 μg/ml.
Application
Immunohistochemistry of TMIGD2 in human small intestine tissue with TMIGD2 antibody at 5 μg/mL.| Positive Control | 1) Cat. No. 1408 - Mouse Small Intestine Tissue Lysate |
|---|---|
| Application Notes | TMIGD2 antibody can be used for detection of TMIGD2 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | TMIGD2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | TMIGD2 antibody is supplied in PBS containing 0.02% sodium azide. |
