This gene encodes the protein trimethyllysine dioxygenase
which is the first enzyme in the carnitine biosynthesis pathway.
Carnitine play an essential role in the transport of activated
fatty acids across the inner mitochondrial membrane. The encoded
protein converts trimethyllysine into hydroxytrimethyllysine. A
pseudogene of this gene is found on chromosome X. Alternate
splicing results in multiple transcript variants.1) Monfregola, J., et al. Gene 395 (1-2), 86-97 (2007) :
Immunogen
This TMLHE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-149 amino acids from the N-terminal region of human TMLHE.
Western blot analysis in HepG2 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.