Application
Western blot analysis of TNFAIP2 in K562 cell lysate with TNFAIP2 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.Application
Immunofluorescence of TNFAIP2 in K562 cells with TNFAIP2 antibody at 20 μg/mL.| Product Name | TNFAIP2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TNFAIP2 Antibody: B94, EXOC3L3, Tumor necrosis factor alpha-induced protein 2, Primary response gene B94 protein, TNF alpha-induced protein 2 |
| Product description | TNFAIP2 Antibody: TNFAIP2, also known as B94, is a TNF-a-regulated gene that is expressed in endothelial cells, peripheral blood cells, and mature sperm. Recently, elevated TNFAIP2 expression was observed in nasopharyngeal carcinoma, and high expression of TNFAIP2 was significantly correlated with higher levels of cell migration, invasion and metastasis, suggesting that TNFAIP2 may serve as a useful prognostic indicator for nasopharyngeal carcinoma. TNFAIP2 has also been implicated as part of the viral-sensing circuit of the innate immune response.1) Wolf FW, Sarma V, Deldin M, et al. B94, a primary response gene inducible by tumor necrosis factor-alpha, is expressed in developing hematopoietic cells and the sperm acrosome. J. Biol. Chem. 1994; 269:3633-40. |
| Immunogen | TNFAIP2 antibody was raised against a 19 amino acid synthetic peptide near the center of human TNFAIP2. The immunogen is located within amino acids 330 - 380 of TNFAIP2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFWB |
| TNFAIP2 antibody can be used for detection of TNFAIP2 by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TNFAIP2 |
|---|---|
| Alternative Names | TNFAIP2 Antibody: B94 EXOC3L3 Tumor necrosis factor alpha-induced protein 2 Primary response gene B94 protein TNF alpha-induced protein 2 |
| Molecular Weight(MW) | 72 kDa |
| Sequence Similarities | 2) Cat. No. 17-004 - K-562 Cell Slide |
| Tissue Specificity | At least two isoforms of TNFAIP2 are known to exist; this antibody will detect both isoforms. This antibody is predicted to not cross-react with TNFAIP3. |
Application
Western blot analysis of TNFAIP2 in K562 cell lysate with TNFAIP2 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Application
Immunofluorescence of TNFAIP2 in K562 cells with TNFAIP2 antibody at 20 μg/mL.| Positive Control | 1) Cat. No. 1204 - K562 Cell Lysate |
|---|---|
| Application Notes | TNFAIP2 antibody can be used for detection of TNFAIP2 by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | TNFAIP2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | TNFAIP2 Antibody is supplied in PBS containing 0.02% sodium azide. |
