Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits JUN/AP1 and NF-kappa-B activation. Promotes Fas-induced apoptosis (By similarity).1) Zhang, G., et al. Mol. Immunol. 47(15):2435-2442(2010)
Immunogen
This TNFAIP8L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-58 amino acids from the N-terminal region of human TNFAIP8L2.
Tumor necrosis factor alpha-induced protein 8-like protein 2 TIPE2 TNF alpha-induced protein 8-like protein 2 TNFAIP8-like protein 2 Inflammation factor protein 20 TNFAIP8L2
Western blot analysis in mouse heart tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.