| Product Name | TNFRSF10A Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TNFRSF10A, DR4, APO2, CD261, TRAILR1, TRAILR-1 |
| Product description | This is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adaptor molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.1) Pan, G. et al (1997) Science 276:111-113.. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TNFRSF10A. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| TNFRSF10A antibody can be used for detection of TNFRSF10A by ELISA at 1:15000. TNFRSF10A antibody can be used for detection of TNFRSF10A by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | TNFRSF10A DR4 APO2 CD261 TRAILR1 TRAILR-1 |
|---|---|
| Molecular Weight(MW) | 50 kDa |
| Protein Accession | NP_003835 |
|---|
| Application Notes | TNFRSF10A antibody can be used for detection of TNFRSF10A by ELISA at 1:15000. TNFRSF10A antibody can be used for detection of TNFRSF10A by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store TNFRSF10A antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
