Application
Antibody used in WB on Human HeLa at 1 ug/ml.| Product Name | TNFRSF18 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TNFRSF18, AITR, GITR, GITR-D, CD357 |
| Product description | The protein encoded by TNFRSF18 is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death.The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.1) Liu, B., (2008) J. Biol. Chem. 283 (13), 8202-8210. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TNFRSF18. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| TNFRSF18 antibody can be used for detection of TNFRSF18 by ELISA at 1:312500. TNFRSF18 antibody can be used for detection of TNFRSF18 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | TNFRSF18 |
|---|---|
| Alternative Names | TNFRSF18 AITR GITR GITR-D CD357 |
| Molecular Weight(MW) | 23 kDa |
Application
Antibody used in WB on Human HeLa at 1 ug/ml.| Positive Control | 1) Cat. No. 1201 - HeLa Cell Lysate |
|---|---|
| Application Notes | TNFRSF18 antibody can be used for detection of TNFRSF18 by ELISA at 1:312500. TNFRSF18 antibody can be used for detection of TNFRSF18 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store TNFRSF18 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
