Application
Antibody used in WB on Human 721_B at 0.2-1 ug/ml.| Product Name | TNFSF12 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TNFSF12, APO3L, DR3LG, MGC129581, MGC20669, TWEAK |
| Product description | TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.1) Park, M.C., (2008) Scand. J. Rheumatol. 37 (3), 173-178. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TNFSF12. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| TNFSF12 antibody can be used for detection of TNFSF12 by ELISA at 1:1562500. TNFSF12 antibody can be used for detection of TNFSF12 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TNFSF12 |
|---|---|
| Alternative Names | TNFSF12 APO3L DR3LG MGC129581 MGC20669 TWEAK |
| Molecular Weight(MW) | 17 kDa |
Application
Antibody used in WB on Human 721_B at 0.2-1 ug/ml.| Positive Control | 1) 721_B Cell Lysate |
|---|---|
| Application Notes | TNFSF12 antibody can be used for detection of TNFSF12 by ELISA at 1:1562500. TNFSF12 antibody can be used for detection of TNFSF12 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store TNFSF12 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
