Application
Immunohistochemistry staining of TNIK in heart tissue using TNIK Antibody.| Product Name | TNIK Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TNIK, ZC2, KIAA0551 |
| Product description | TNIK is a MSN protein kinase that interacts with both TNF receptor-associated factor 2 (TRAF2) and the adapter protein NCK. The protein has been shown to activate the c-Jun N-terminal kinase pathway when overexpressed in Phoenix-A cells, and this activation is mediated solely by the C-terminal germinal center kinase homology region. TNIK has been shown to phosphorylate gelsolin, the principal intracellular and extracellular actin-severing protein, in vitro. This and evidence from mutational studies suggest that TNIK functions in the regulation of the cytoskeleton. At least eight splice isoforms have been reported. |
| Immunogen | TNIK antibody was raised against a peptide located near the internal domain of TNIK (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHC |
| TNIK antibody can be used in immunohistochemistry starting at 30 μg/mL.: |
|
| Species Reactivity | GibbonGorillaHumanMonkey |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TNIK |
|---|---|
| Alternative Names | TNIK ZC2 KIAA0551 |
| Tissue Specificity | BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Application
Immunohistochemistry staining of TNIK in heart tissue using TNIK Antibody.| Application Notes | TNIK antibody can be used in immunohistochemistry starting at 30 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | TNIK antibody should be stored long term (months) at -80 ˚C and short term (days) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.1% sodium azide. |
