TNIP2, ABIN-2, ABIN2, FLIP1, KLIP, TNFAIP3-interacting protein 2, TNFAIP3 interacting protein 2
Product description
ABIN-2 binds to the COOH-terminal zinc finger domain of A20. NF-κB activation induced by TNF and interleukin-1 is inhibited by overexpression of ABIN-2. The latter also inhibits NF-κB activation induced by overexpression of receptor-interacting protein or TNF receptor-associated factor 2. A-20 binding Inhibitor of Nuclear Factor-kappaB (NF-κB)Activation (ABIN-2) binds to A-20. ABIN-2 interferes with NF-κB activation upstream of the IKK complex and might contribute to NF-κB inhibitory function of A-20.
Immunogen
TNIP2 antibody was raised against synthetic peptides of TNIP2 (Human).
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCWB
TNimmunoprecipitation2 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 2.5 μg/mL.: