This gene encodes a leucine-rich transmembrane
glycoprotein that may be involved in cell adhesion. The encoded
protein is an oncofetal antigen that is specific to trophoblast
cells. In adults this protein is highly expressed in many tumor
cells and is associated with poor clinical outcome in numerous
cancers. Alternate splicing in the 5' UTR results in multiple
transcript variants that encode the same protein. [provided by
RefSeq].1) Elkord, E., et al. J. Immunother. 31(9):820-829(2008)
Immunogen
This TPBG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-197 amino acids from the Central region of human TPBG.
Western blot analysis in A2058 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.