Application
Antibody used in WB on Human HeLa at 0.2-1 ug/ml.| Product Name | TRAF4 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TRAF4, CART1, MLN62, RNF83 |
| Product description | TRAF4 is a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. It has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD (P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK.This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD (P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.1) Sawzdargo, M., (2007) Oncogene 26 (1), 142-147. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TRAF4. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| TRAF4 antibody can be used for detection of TRAF4 by ELISA at 1:62500. TRAF4 antibody can be used for detection of TRAF4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TRAF4 |
|---|---|
| Alternative Names | TRAF4 CART1 MLN62 RNF83 |
| Molecular Weight(MW) | 53 kDa |
Application
Antibody used in WB on Human HeLa at 0.2-1 ug/ml.| Positive Control | 1) Cat. No. 1201 - HeLa Cell Lysate |
|---|---|
| Application Notes | TRAF4 antibody can be used for detection of TRAF4 by ELISA at 1:62500. TRAF4 antibody can be used for detection of TRAF4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store TRAF4 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
