| Product Name | TRAM Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TRIF-related Adapter Molecule; TIRP; Toll-Interleukin 1 Receptor [TIR] Domain-containing Protein; TICAM-2; TIR-containing Adapter Molecule-2 |
| Product description | TRAM functions in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. It is also involved in IL-1-triggered NF-kappaB activation, functioning upstream of IRAK1, IRAK2, TRAF6 and IKBKB. TRAM physically bridges TLR4 and TICAM-1 and functionally transmits LPS-TRL4 signal to TICAM-1. It is expressed in spleen, prostate, testis, uterus, small intestine, colon, peripheral blood leukocytes, heart, placenta, lung, liver, skeletal muscle and pancreas. |
| Immunogen | Synthetic peptide corresponding to aa 2-29 (G2IGKSKINSCPLSLSWGKRHSVDTSPGY29) of human TRAM. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: (1:1,000).: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Symbol | TICAM2 |
|---|---|
| Alternative Names | TRIF-related Adapter Molecule TIRP Toll-Interleukin 1 Receptor [TIR] Domain-containing Protein TICAM-2 TIR-containing Adapter Molecule-2 |
| Tissue Specificity | Recognizes human TRAM. |
| Application Notes | Western Blot: (1:1,000).: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Stable for at least 1 year after receipt when stored at -20˚C. |
| Storage Buffer | Liquid. Neat serum containing 0.02% sodium azide. |
