Application
Western blot analysis of TGM2 using rabbit polyclonal using 293 cell lysates (2 ug/lane) either nontransfected (c) or transiently transfected with the TGM2 gene (Lane 2).| Product Name | Transglutaminase Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Protein-glutamine gamma-glutamyltransferase 2, Tissue transglutaminase, Transglutaminase C, TG(C), TGC, TGase C, Transglutaminase H, TGase H, Transglutaminase-2, TGase-2, TGM2 |
| Product description | Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. TGM2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. It has been identified as the autoantigen implicated in celiac disease.1) Porzio,O., Hum. Mutat. 28 (11), 1150 (2007) |
| Immunogen | This Transglutaminase (TGM2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 413-442 amino acids from the Central region of human Transglutaminase (TGM2). |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Symbol | TGM2 |
|---|---|
| Alternative Names | Protein-glutamine gamma-glutamyltransferase 2 Tissue transglutaminase Transglutaminase C TG(C) TGC TGase C Transglutaminase H TGase H Transglutaminase-2 TGase-2 TGM2 |
| Molecular Weight(MW) | 77 kDa |
Application
Western blot analysis of TGM2 using rabbit polyclonal using 293 cell lysates (2 ug/lane) either nontransfected (c) or transiently transfected with the TGM2 gene (Lane 2).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
