Trem-like transcript 1 protein, TLT-1, Triggering receptor expressed on myeloid cells-like protein 1, TREML1, TLT1
Product description
TREML1 is located in a gene cluster on chromosome 6 with
the single Ig variable (IgV) domain activating receptors TREM1 (MIM
605085) and TREM2 (MIM 605086), but it has distinct structural and
functional properties. TREML1 enhances calcium signaling in an SHP2
(PTPN11; MIM 176876)-dependent manner (Allcock et al., 2003 [PubMed
12645956]; Barrow et al., 2004 [PubMed 15128762]).[supplied by
OMIM].1) Morales, J., et al. Blood Coagul. Fibrinolysis 21(3):229-236(2010)
Immunogen
This TREML1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-241 amino acids from the C-terminal region of human TREML1.
Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
Application
Western blot analysis in mouse spleen tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.