E3 ubiquitin-protein ligase TRIM68, 632-, RING finger protein 137, SSA protein SS-56, SS-56, Tripartite motif-containing protein 68, TRIM68, GC109, RNF137, SS56
Product description
The protein encoded by this gene contains a RING finger
domain, a motif present in a variety of functionally distinct
proteins and known to be involved in protein-protein and
protein-DNA interactions. This gene is expressed in many cancer
cell lines. Its expression in normal tissues, however, was found to
be restricted to prostate. This gene was also found to be
differentially expressed in androgen-dependent versus
androgen-independent prostate cancer cells.1) Malhotra, A., et al. Diabetes Metab. Res. Rev. 25(8):740-747(2009)
Immunogen
This TRIM68 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 382-411 amino acids from the C-terminal region of human TRIM68.
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.