Application
Immunohistochemical analysis of paraffin-embedded H. brain section using TrkC Antibody. Antibody was diluted at 1:100 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.Application
Western blot analysis in U87-MG cell line lysates (35ug/lane).| Product Name | TrkC Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NT-3 growth factor receptor, GP145-TrkC, Trk-C, Neurotrophic tyrosine kinase receptor type 3, TrkC tyrosine kinase, NTRK3, TRKC |
| Product description | TRKC, a member of the insuline receptor subfamily of Tyr protein kinases, is a receptor for neurotrophin-3 (NT-3). Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. The protein is widely expressed, mainly in the nervous tissue. The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain. TRKC is subject to ligand-mediated auto-phosphorylation. The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats.1) McGregor, L.M., et al., Genomics 22(2):267-272 (1994). |
| Immunogen | This TrkC antibody is generated from rabbits immunized with a his tag recombinant protein of human TrkC. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| For IHC-P starting dilution is: 1:100 For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Symbol | NTRK3 |
|---|---|
| Alternative Names | NT-3 growth factor receptor GP145-TrkC Trk-C Neurotrophic tyrosine kinase receptor type 3 TrkC tyrosine kinase NTRK3 TRKC |
| Molecular Weight(MW) | 94 kDa |
Application
Immunohistochemical analysis of paraffin-embedded H. brain section using TrkC Antibody. Antibody was diluted at 1:100 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.
Application
Western blot analysis in U87-MG cell line lysates (35ug/lane).| Application Notes | For IHC-P starting dilution is: 1:100 For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
