Application
Western blot analysis of lysed extracts from A549 and mouse brain tissue using TRPC6 Antibody.| Product Name | TRPC6 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).1) Koichiro Kuwahara et al. (2006) J Clin Invest. 116 (12): 3114–3126. Mark Estacion et al. (2006) J Physiol. 2006, 572 (Pt 2): 359–377. Maria A et al. (2006) Proc Natl Acad Sci U S A. 103 (44): 16586–16591. |
| Immunogen | TRPC6 antibodypeptide Corresponding to the amino terminal sequence derived from mouse TRPC6. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TRPC6 |
|---|---|
| Alternative Names | TRP6 FSGS2 TRP6 FLJ11098 |
| Molecular Weight(MW) | 100 kDa |
| Tissue Specificity | This antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Entrez Gene | 7225 |
|---|---|
| Protein Accession | NP_004612.2 |
Application
Western blot analysis of lysed extracts from A549 and mouse brain tissue using TRPC6 Antibody.| Application Notes | Western Blot: 1:500~1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
