Transient receptor potential vanilloid (TRPV) channels are widely expressed in both sensory and nonsensory cells. TRPV2, a member of transient receptor potential ion channels, responds to high-threshold noxious heat (with a threshold of approximately 52 degrees C), but neither to capsaicin nor to proton. TRPV2 transcripts are not restricted to the sensory nervous system, indicating that this channel may be activated by stimuli other than heat. It has been proposed that responses to noxious heat involve these related, but distinct, ion-channel subtypes that together detect a range of stimulus intensities.
Immunogen
TRPV2 antibody was raised against a peptide located in the N-Terminal domain of TRPV2 (Human).
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
IHC
TRPV2 antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, immunohistochemistry starting at 1:200 - 1:400, and immunofluorescence starting at 1:200 - 1:1000.
Immunohistochemistry staining of TRPV2 in dorsal root ganglion tissue using TRPV2 Antibody.
Application Notes
TRPV2 antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, immunohistochemistry starting at 1:200 - 1:400, and immunofluorescence starting at 1:200 - 1:1000.
Additional Information
Form
Liquid
Storage Instructions
TRPV2 antibody should be stored long term (months) at -80 ˚C and short term (days) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles.