Application
Western blot analysis of TSHZ1 in A-20 cell lysate with TSHZ1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.Application
Immunofluorescence of TSHZ1 in A20 cells with TSHZ1 antibody at 20 μg/mL.Application
Immunocytochemistry of TSHZ1 in A20 cells with TSHZ1 antibody at 2.5 μg/mL.| Product Name | TSHZ1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | TSHZ1 Antibody: The Teashirt zinc finger homeobox (TSHZ) family comprise a family of evolutionarily conserved transcription factors that, in Drosophila, are active in specific body parts for patterning, but whose function in vertebrates is less clear. TSHZ1 has been found to be required for axial skeleton, soft palate and middle ear development in mice and may be involved in a common pathway with the Hox genes. Both TSHZ1 and the related protein TSHZ3 have been found to interact with FE65, an adapter protein that binds to the amyloid protein precursor (APP) in neurons. Together with SET, a component of the inhibitor of acetyl transferase, and histone deacetylases, these proteins formed a gene-silencing complex whose target includes caspase-4.1) Caubit X, Core N, Boned A, et al. Vertebrate orthologues of the Drosophila region-specific patterning gene teashirt. Mech. Dev. 2000; 91:445-8. |
| Immunogen | TSHZ1 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human TSHZ1. The immunogen is located within amino acids 70 - 120 of TSHZ1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAICCIFWB |
| TSHZ1 antibody can be used for detection of TSHZ1 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μg/mL. For immunofluorescence start at 2.5 μg/mL. | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TSHZ1 |
|---|---|
| Alternative Names | TSHZ1 Antibody: CAA TSH1 NY-CO-33 SDCCAG33 Teashirt homolog 1 Antigen NY-CO-33 |
| Sequence Similarities | 2) Cat. No. 17-208 - A-20 Cell Slide |
Application
Western blot analysis of TSHZ1 in A-20 cell lysate with TSHZ1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Application
Immunofluorescence of TSHZ1 in A20 cells with TSHZ1 antibody at 20 μg/mL.
Application
Immunocytochemistry of TSHZ1 in A20 cells with TSHZ1 antibody at 2.5 μg/mL.| Positive Control | 1) Cat. No. 1288 - A20 Cell Lysate |
|---|---|
| Application Notes | TSHZ1 antibody can be used for detection of TSHZ1 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μg/mL. For immunofluorescence start at 2.5 μg/mL. |
| Form | Liquid |
|---|---|
| Storage Instructions | TSHZ1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | TSHZ1 Antibody is supplied in PBS containing 0.02% sodium azide. |
