Application
Western blot analysis of TSLP Receptor in human liver tissue lysate with TSLP Receptor antibody at (A) 0.5, (B) 1 and (C) 2 μg/mL.Application
Immunofluorescence of TSLP Receptor in Human Liver tissue with TSLP Receptor antibody at 20 μg/mL.Application
Immunohistochemistry of TSLP-R in human liver tissue with TSLP-R antibody at 5 μg/mL.| Product Name | TSLP Receptor Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TSLP Receptor Antibody: CRLM2, Ly114, Tpte2, Tslpr, Crlm2, Cytokine receptor-like factor 2, Cytokine receptor-like molecule 2, CRLM-2 |
| Product description | TSLP Receptor Antibody: Thymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable of driving dendritic cell maturation and activation. It is involved in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and the induction of CD4+ T cell-mediated allergic reaction. TSLP is also capable of supporting the growth of fetal liver and adult B cell progenitors and their differentiation to the IgM-positive stage of B cell development. Its receptor TSLP-R will bind TSLP in a low-affinity fashion in transfected cells; co-transfection with IL-7R-alpha cDNA results in high-affinity binding and a functional heteromeric complex. This heteromeric receptor requires stat5 for TSLP-mediated signal transduction and is inhibited by SOCS-1.1) Ziegler SF and Liu Y-J. Thymic stromal lymphopoietin in normal and pathogenic T cell development and function. Nature Immunol. 2006; 7:709-14. |
| Immunogen | TSLP Receptor antibody was raised against a 19 amino acid synthetic peptide from near the center of human TSLP receptor. The immunogen is located within amino acids 140 - 190 of TSLP Receptor. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| TSLP-R antibody can be used for detection of TSLP-R by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Crlf2 |
|---|---|
| Alternative Names | TSLP Receptor Antibody: CRLM2 Ly114 Tpte2 Tslpr Crlm2 Cytokine receptor-like factor 2 Cytokine receptor-like molecule 2 CRLM-2 |
| Molecular Weight(MW) | Predicted: 28, 41 kDa Observed: 53 kDa |
| Sequence Similarities | 2) Cat. No. 10-201 - Human Liver Tissue Slide |
| Tissue Specificity | At least two isoforms of TSLP-R are known to exist; this antibody will recognize both isoforms. |
Application
Western blot analysis of TSLP Receptor in human liver tissue lysate with TSLP Receptor antibody at (A) 0.5, (B) 1 and (C) 2 μg/mL.
Application
Immunofluorescence of TSLP Receptor in Human Liver tissue with TSLP Receptor antibody at 20 μg/mL.
Application
Immunohistochemistry of TSLP-R in human liver tissue with TSLP-R antibody at 5 μg/mL.| Positive Control | 1) Cat. No. 1304 - Human Liver Tissue Lysate |
|---|---|
| Application Notes | TSLP-R antibody can be used for detection of TSLP-R by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | TSLP Receptor antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | TSLP Receptor Antibody is supplied in PBS containing 0.02% sodium azide. |
