Tetratricopeptide repeat protein 8, TPR repeat protein 8, Bardet-Biedl syndrome 8 protein, TTC8, BBS8
Product description
This gene encodes a protein that has been directly linked
to Bardet-Biedl syndrome. The primary features of this syndrome
include retinal dystrophy, obesity, polydactyly, renal
abnormalities and learning disabilities. Experimentation in
non-human eukaryotes suggests that this gene is expressed in
ciliated cells and that it is involved in the formation of cilia.
Alternate transcriptional splice variants have been characterized.1) Riazuddin, S.A., et al. Am. J. Hum. Genet. 86(5):805-812(2010)
Immunogen
This TTC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the N-terminal region of human TTC8.
Western blot analysis in 293 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.