The protein encoded by this gene localizes to the
centrosome during mitosis and to the midbody during cytokinesis.
The protein is phosphorylated by cyclin-dependent kinase 1 during
mitosis and subsequently interacts with polo-like kinase 1. The
protein is thought to function in regulating mitosis and
cytokinesis. Mutations in this gene result in nonphotosensitive
trichothiodystrophy.1) Zhang, Y., et al. Cell. Mol. Life Sci. 64(5):632-640(2007)
Immunogen
This TTDN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-177 amino acids from the C-terminal region of human TTDN1.
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.