Alpha-tocopherol transfer protein, Alpha-TTP, TTPA, TPP1
Product description
This gene encodes a soluble protein that binds
alpha-trocopherol, a form of vitamin E, with high selectivity and
affinity. This protein plays an important role in regulating
vitamin E levels in the body by transporting vitamin E between
membrane vesicles and facilitating the secretion of vitamin E from
hepatocytes to circulating lipoproteins. Mutations in this gene
cause hereditary vitamin E deficiency (ataxia with vitamin E
deficiency, AVED) and retinitis pigmentosa.1) Zhang, W.X., et al. Lipids 44(7):631-641(2009)
Immunogen
This TTPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-108 amino acids from the Central region of human TTPA.
Western blot analysis in CEM cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.