Application
Western blot analysis of TYK2 in human small intestine tissue lysate with TYK2 antibody at (A) 1 and (B) 2 μg/mL| Product Name | TYK2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TYK2 Antibody: JTK1, Non-receptor tyrosine-protein kinase TYK2 |
| Product description | TYK2 Antibody: TYK2 is a member of the Janus kinases (JAKs) protein families. TYK2 associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits and is also a component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.1) Strobl B, Stoiber D, Sexl V, et al. Tyrosine kinase 2 (TYK2) in cytokine signalling and host immunity. Front. Biosci. 2011; 17:3214-32. |
| Immunogen | Rabbit polyclonal TYK2 antibody was raised against a 17 amino acid peptide near the amino terminus of human TYK2. The immunogen is located within amino acids 90 - 140 of TYK2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| TYK2 antibody can be used for detection of TYK2 by Western blot at 1 - 2 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TYK2 |
|---|---|
| Alternative Names | TYK2 Antibody: JTK1 Non-receptor tyrosine-protein kinase TYK2 |
| Molecular Weight(MW) | Predicted: 131 kDa |
| Tissue Specificity | At least three isoforms of TYK2 are known to exist; this antibody only detects the two longest isoforms. |
Application
Western blot analysis of TYK2 in human small intestine tissue lysate with TYK2 antibody at (A) 1 and (B) 2 μg/mL| Positive Control | 1) Cat. No. 1308 - Human Small Intestine Tissue Lysate |
|---|---|
| Application Notes | TYK2 antibody can be used for detection of TYK2 by Western blot at 1 - 2 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | TYK2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | TYK2 Antibody is supplied in PBS containing 0.02% sodium azide. |
