Application
Western blot analysis of lysate from U-87 MG cell line, using TYRO3 Antibody at 1:1000 at each lane.Application
Formalin-fixed and paraffin-embedded human brain tissue reacted with TYRO3 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.| Product Name | TYRO3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Tyrosine-protein kinase receptor TYRO3, Tyrosine-protein kinase BYK, Tyrosine-protein kinase DTK, Tyrosine-protein kinase RSE, Tyrosine-protein kinase SKY, Tyrosine-protein kinase TIF, TYRO3, BYK, DTK, RSE, SKY, TIF |
| Product description | Tyrosine kinase 3,mainly expressed in brain,is involved in the protection of neurons from apoptosis. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.1) Dey, B.R., et al., Gene 209 (1-2), 175-183 (1998). |
| Immunogen | This TYRO3 antibody is generated from rabbits immunized with human recombinant TYRO3 protein. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Symbol | TYRO3 |
|---|---|
| Alternative Names | Tyrosine-protein kinase receptor TYRO3 Tyrosine-protein kinase BYK Tyrosine-protein kinase DTK Tyrosine-protein kinase RSE Tyrosine-protein kinase SKY Tyrosine-protein kinase TIF TYRO3 BYK DTK RSE SKY TIF |
| Molecular Weight(MW) | 97 kDa |
Application
Western blot analysis of lysate from U-87 MG cell line, using TYRO3 Antibody at 1:1000 at each lane.
Application
Formalin-fixed and paraffin-embedded human brain tissue reacted with TYRO3 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.| Application Notes | For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
