Application
Immunofluorescence staining of methanol-fixed HeLa cells using Tyrosine Hydroxylase (Phospho-Ser40).| Product Name | Tyrosine Hydroxylase (phospho Ser40) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TYH, DYT14, DYT5b, MAPTL, MTBT1, TAU, TY3H, TYH, Tyrosine 3-hydroxylase, tyrosine hydroxylase |
| Product description | The protein encoded by Tyrosine Hydroxylase is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.1) Vazin T, et al. Stem Cells. 2008 Jun;26 (6): 1517-25Pistocchi A, et al. BMC Dev Biol. 2008 Mar 10;8:27 Fukakusa A, et al. J Pharmacol Sci. 2008 Feb;106 (2): 321-4. |
| Immunogen | Tyrosine Hydroxylase (Phospho-Ser40) antibody was raised against a peptide sequence around phosphorylation site of serine 40 (R-Q-S (p) -L-I) derived from Human Tyrosine Hydroxylase (TH). |
| Modification | p-Ser40 |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IF |
| Immunofluorescence: 1:100~1:200: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TH |
|---|---|
| Alternative Names | TYH DYT14 DYT5b MAPTL MTBT1 TAU TY3H TYH Tyrosine 3-hydroxylase tyrosine hydroxylase |
| Molecular Weight(MW) | 55 - 60 kDa |
| Tissue Specificity | This antibody detects endogenous level of TyrosineHydroxylase only when phosphorylated at serine 40. |
| Entrez Gene | 7054 |
|---|---|
| Protein Accession | NP_000351.2 |
Application
Immunofluorescence staining of methanol-fixed HeLa cells using Tyrosine Hydroxylase (Phospho-Ser40).| Application Notes | Immunofluorescence: 1:100~1:200: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
