Ubiquitin-conjugating enzyme E2 Q1, Protein NICE-5, Ubiquitin carrier protein Q1, Ubiquitin-protein ligase Q1, UBE2Q1, NICE5, UBE2Q
Product description
The modification of proteins with ubiquitin is an
important cellular mechanism for targeting abnormal or short-lived
proteins for degradation. Ubiquitination involves at least three
classes of enzymes: ubiquitin-activating enzymes (E1s),
ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases
(E3s). This gene encodes a member of the E2 ubiquitin-conjugating
enzyme family. The encoded protein is 98% identical to the mouse
counterpart.1) Wassler, M.J., et al. Stem Cells 26(8):2006-2018(2008)
Immunogen
This UBE2Q1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-104 amino acids from the N-terminal region of human UBE2Q1.
Western blot analysis in Jurkat cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.