Application
Western blot analysis of UBIAD1 in mouse liver tissue lysate with UBIAD1 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.Application
Immunofluorescence of UBIAD1 in mouse liver tissue with UBIAD1 antibody at 20 μg/mL.Application
Immunohistochemistry of UBIAD1 in mouse liver tissue with UBIAD1 antibody at 5 μg/mL.| Product Name | UBIAD1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | UBIAD1 Antibody: SCCD, TERE1, UbiA prenyltransferase domain-containing protein 1, Transitional epithelial response protein 1 |
| Product description | The UbiA prenyltransferase domain containing 1 (UBIAD1) protein , also known as TERE1, was initially identified as a down-regulated gene in transitional cell carcinoma of the bladder (1). Recently it has been shown to bind the cholesterol carrier APOE and modulate cellular cholesterol levels (2). Mutations in the UBIAD1 gene can cause Schnyder crystalline corneal dystrophy, an autosomal dominant disease characterized by progressive opacification of the cornea resulting from the local accumulation of lipids (3).1) McGarvey TW, Nguyen T, Tomaszewski JE, et al. Isolation and characterization of TERE1 gene, a gene down-regulated in transitional cell carcinoma of the bladder. Oncogene 2001; 20:1042-51. |
| Immunogen | UBIAD1 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human UBIAD1. The immunogen is located within amino acids 210 - 260 of UBIAD1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| UBIAD1 antibody can be used for detection of UBIAD1 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry at 5 μg/mL. For Immunoflorescence start at 20 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | UBIAD1 |
|---|---|
| Alternative Names | UBIAD1 Antibody: SCCD TERE1 UbiA prenyltransferase domain-containing protein 1 Transitional epithelial response protein 1 |
| Molecular Weight(MW) | Predicted: 37 kDa Observed: 45 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Chicken: (87%) |
| Tissue Specificity | UBIAD1 antibody is human, mouse and rat reactive. |
Application
Western blot analysis of UBIAD1 in mouse liver tissue lysate with UBIAD1 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.
Application
Immunofluorescence of UBIAD1 in mouse liver tissue with UBIAD1 antibody at 20 μg/mL.
Application
Immunohistochemistry of UBIAD1 in mouse liver tissue with UBIAD1 antibody at 5 μg/mL.| Positive Control | 1) Cat. No. 1404 - Mouse Liver Tissue Lysate |
|---|---|
| Application Notes | UBIAD1 antibody can be used for detection of UBIAD1 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry at 5 μg/mL. For Immunoflorescence start at 20 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | UBIAD1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | UBIAD1 Antibody is supplied in PBS containing 0.02% sodium azide. |
