Application
Western blot analysis of UROP11 in mouse spleen tissue lysate with UROP11 antibody at (A) 1 and (B) 2 μg/mL.| Product Name | UROP11 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | UROP11 Antibody: X11, Mint, Mint1, Lin-10, Urop11, X11alpha, 6430513E09Rik, X11, Amyloid beta A4 precursor protein-binding family A member 1, Adapter protein X11alpha, Mint-1 |
| Product description | UROP11 Antibody: Upregulated obese product 11 (UROP11) was isolated from subtractive library for mouse hypothalamus. It is detected in numerous tissues and is upregulated in the hypothalamus and adipocytes in obese mice. UROP11 is also observed in human neural and lymphoid tissues; its expression appears to be regulated by the level of lymphoid activation. Urop11 expression is strongly upregulated both in vivo in mouse hypothalamus and in vitro in mouse neural cell lines after treatment with leptin, indicating Urop11 is a target of leptin activity and thus may play a role in obesity.1) Verlaeten O, Casery C, Cavagna S, et al. Identification of Urop11, a novel leptin-modulated gene that is upregulated in the hypothalamus of mice with virus-induced obesity. J. Mol. Endocrinol.2007; 38:3-17. |
| Immunogen | UROP11 antibody was raised against a 12 amino acid synthetic peptide near the center of the mouse UROP11. The immunogen is located within the first 50 amino acids of UROP11. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| UROP11 antibody can be used for detection of UROP11 by Western blot at 1 - 2 μg/mL. Despite its predicted molecular weight, UROP11 often migrates at a much higher apparent size in SDS-PAGE.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Apba1 |
|---|---|
| Alternative Names | UROP11 Antibody: X11 Mint Mint1 Lin-10 Urop11 X11alpha 6430513E09Rik X11 Amyloid beta A4 precursor protein-binding family A member 1 Adapter protein X11alpha Mint-1 |
Application
Western blot analysis of UROP11 in mouse spleen tissue lysate with UROP11 antibody at (A) 1 and (B) 2 μg/mL.| Positive Control | 1) Cat. No. 1406 - Mouse Spleen Tissue Lysate |
|---|---|
| Application Notes | UROP11 antibody can be used for detection of UROP11 by Western blot at 1 - 2 μg/mL. Despite its predicted molecular weight, UROP11 often migrates at a much higher apparent size in SDS-PAGE.: |
| Form | Liquid |
|---|---|
| Storage Instructions | UROP11 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | UROP11 Antibody is supplied in PBS containing 0.02% sodium azide. |
